Girma Zewdie Delelegn

Girma Zewdie
Delelegn

Veterinary Vaccine production chief officer
National Veterinary Institute and PhD candidate at Addis Ababa University
Email 
giema.zewdie [at] nvi.com.et
Biography
I am Girma Zewdie, the chief officer of vaccine production at NVI, Ethiopia, and a PhD candidate at Addis Ababa University. My career spans over 11 years, focusing on animal vaccine development and production. I am dedicated to enhancing animal health and veterinary medicine through effective collaboration and innovation.
Research interests
My research is dedicated to vaccine development for livestock and zoonotic diseases within the realms of virology and bacteriology. I focus on neglected zoonotic pathogens such as brucellosis and leishmaniasis, as well as trans-boundary viral diseases affecting livestock, including Capripoxviruses, FMDV, and PPRV. The goal of my work is to mitigate the health and economic repercussions of these diseases, thereby bolstering food security.
Projects you're working on
I am working on a project to produce a gamma-ray inactivated LSD vaccine for cattle, which is a safe and effective way to prevent lumpy skin disease, a viral infection that causes skin nodules and reduced milk production in cattle. I am also studying the molecular epidemiology of the LSD virus to understand its genetic variation, evolution, and transmission patterns in different regions and countries. My project involves developing and testing a gamma-ray inactivated LSD vaccine for cattle, which is a novel method of killing the virus while preserving its antigenicity. This vaccine can protect cattle from lumpy skin disease, a serious disease that affects the skin, lymph nodes, and milk production of cattle. I am also conducting molecular epidemiology analysis of the LSD virus to investigate its origin, diversity, and recombination events in various geographical areas and populations. The aim of my project is to create a gamma-ray inactivated LSD vaccine for cattle, which is a technique that uses ionizing radiation to inactivate the virus but maintain its immunogenicity. This vaccine can help to control lumpy skin disease, a contagious disease that causes skin lesions and economic losses in cattle. I am also doing molecular epidemiology research on the LSD virus to examine its genetic diversity, evolution, and epidemiology in different settings and hosts.
Discipline
Bacteriology Bio-manufacturing Challenge study design Clinical trials – efficacy Clinical trials – safety Molecular biology Virology
Host species
Cattle Poultry Small ruminants
Pathogen
BacteriaBrucella BacteriaSalmonella Viruses VirusesCapripoxvirus VirusesFoot-and-mouth disease virus VirusesNewcastle disease virus
Stage of vaccine development
Field trials Pre-clinical trials