Alan Young

Professor
Alan
Young

Professor, Veterinary and BIomedical Sciences, South Dakota State University; Chief Technology Officer and Founder, Medgene, Brookings, SD. USA
Medgene, South Dakota State University
Email 
alan.young [at] medgenelabs.com
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Biography
Dr. Young’s career has focused on the application of domestic animal models to biomedical applications. Dr. Young received his BSc and PhD in Immunology from the University of Toronto, focusing on the role of the migratory immune system in defense against disease. Following postdoctoral training in lymphatic physiology, Dr. Young took a position as Scientific Member of the Ruminant Immunology Laboratory at the Basel Institute for Immunology. Following closure of the Institute, Dr. Young accepted a faculty position in the Department of Surgery at Harvard Medical School, prior to moving to his current position at the Department of Veterinary and Biomedical Sciences at South Dakota State University. Dr. Young has served as the lead on academic initiatives designed to promote cross-institutional and academic-industry collaborations, including founding the Multistate Research Committee to deal with BSE in the United States and as a Co-PI for development of a Rift Valley Fever vaccine through the Center of Emerging Zoonoses and Animal Diseases at Kansas State University. His training as an Immunologist focuses much of his work on the response of domestic animals to emerging and zoonotic diseases, and the application of animal models to development of new therapies, diagnostics, and research models for human disease. Since 2004, Dr. Young has been an active participant in translational technology development, authoring and supervising several successful Phase I and Phase II SBIR projects in collaboration with Federal Laboratories and Academic Institutions within the United States and Canada. In 2011, Dr. Young founded VST/Medgene Labs to assist in the translation of early stage technologies to the marketplace and to develop new vaccine and diagnostic tools for human and veterinary medicine. Medgene Labs is a USDA-licensed firm for production of both Autogenous and Prescription-Platform vaccines, with commercial products providing solutions for swine and cattle, with additional products serving the needs of minor species such as deer, rabbits, and bison. In addition to these commercially relevant products, Medgene’s platform is also being applied towards solutions for Foreign Animal Diseases, including Rift Valley Fever, Classical Swine Fever, Nipah Virus, and Highly Pathogenic Avian Influenza.
Research interests
Subunit Vaccines, Platform Vaccines, Foreign Animal Disease Vaccines, Emerging Diseases.
Projects you're working on
Subunit vaccines for veterinary species - primary commercialized targets include caliciviruses, rotavirus, bunyaviruses, orbiviruses, papillomaviruses, tick vaccines, influenza, parainfluenza, pestiviruses, circoviruses, coronaviruses.
Discipline
Bio-manufacturing Bioinformatics Challenge study design Clinical trials – efficacy Clinical trials – safety Commercialisation Formulation technology Immunology – B-cells Immunology – T-cells Immunology – innate Protein biology Regulation Virology
Host species
Buffalo Cats Cattle Dogs Fish Pigs Poultry Small ruminants Wildlife Zoonoses
Pathogen
Bacteria BacteriaErysipelas BacteriaMycobacteria bovis BacteriaMycoplasma Parasites ParasitesBabesia ParasitesTicks Viruses VirusesAdenovirus VirusesAfrican horse sickness virus VirusesAfrican swine fever virus VirusesArboviruses VirusesBluetongue virus VirusesBovine viral diarrhoea VirusesCalicivirus VirusesClassical swine fever virus VirusesCoronavirus VirusesInfectious salmon anaemia virus VirusesInfluenza virus VirusesNipah virus VirusesParainfluenza virus VirusesParvovirus VirusesPorcine circovirus VirusesPoxviruses VirusesRespiratory syncytial virus VirusesRift Valley fever virus VirusesRotavirus
Stage of vaccine development
Antigen discovery and immunogen design Commercialisation