 
Biography
        
My name is Karina Pasquevich, and I am an Argentinian scientist, born in La Plata on June 13, 1978. I earned my degree in Biochemistry from the National University of La Plata in 2003 and completed my Ph.D. in Immunology at the University of Buenos Aires in 2009. My doctoral research, under the supervision of Dr. Juliana Cassataro, focused on the development of vaccines for Brucellosis and was carried out at the Institute of Humoral Immunity Research (IDEHU) and the Immunogenetics Laboratory at the Hospital de Clínicas, UBA.
Between 2010 and 2011, I worked as a postdoctoral fellow at the University of Tübingen in Germany, with funding from the Alexander von Humboldt Foundation. During that time, I studied bacterial infections and their effects on immune cell development.
In 2012, I joined Dr. Cassataro’s group as an assistant researcher at CONICET, and I currently work as an independent researcher at the Institute for Biotechnology Research (IIB-INTECH) at the National University of San Martín. Since the beginning of my scientific career, I have focused on vaccine development, with a particular interest in the design and application of novel vaccine adjuvants.
I have published 38 peer-reviewed scientific papers, co-authored two patents on vaccine adjuvants (one granted, one pending), and led three research grants as principal investigator. I have also been actively involved in the development of ARVAC, a recombinant subunit vaccine against COVID-19, which has been approved for human use in Argentina.  Research interests
        My research interests lie in the field of immunology, with a strong focus on vaccine development. I am particularly interested in the design, characterization, and application of novel adjuvants, especially mucosal adjuvants, to enhance vaccine efficacy. A key part of my work involves testing these adjuvants in various vaccine formulations and delivery routes to elicit robust and protective immune responses. I am also interested in the immune response to both bacterial and viral infections, as well as the responses induced by vaccination, with a special focus on the effector functions of antibodies.  Projects you're working on
        I am currently working on the structure–activity relationship of mucosal vaccine adjuvants, aiming to understand how their molecular features influence immune activation and efficacy. In parallel, I am involved in evaluating the immunogenicity of various vaccine formulations, both in preclinical models and in clinical trial samples, to identify correlates of protection and improve vaccine design.  Discipline
        Bacteriology      Challenge model development      Clinical trials – efficacy      Clinical trials – safety      Formulation technology      Immunology – B-cells      Immunology – T-cells      Immunology – innate      Structural biology  Host species
        Cattle      Fish      Pigs      Poultry      Small ruminants      Zoonoses  Pathogen
        Bacteria      Bacteria›Brucella      Bacteria›Chlamydophila      Bacteria›Clostridia      Bacteria›E. coli      Bacteria›Leptospira      Bacteria›Mycobacteria bovis      Bacteria›Salmonella      Bacteria›Yersinia      Parasites      Viruses      Viruses›Adenovirus      Viruses›African swine fever virus      Viruses›Arboviruses      Viruses›Arteriviruses      Viruses›Avian papillomavirus      Viruses›Avian polyomavirus      Viruses›Bluetongue virus      Viruses›Bovine ephemeral fever virus      Viruses›Bovine viral diarrhoea      Viruses›Capripoxvirus      Viruses›Chicken anaemia virus      Viruses›Classical swine fever virus      Viruses›Coronavirus      Viruses›Cytomegalovirus      Viruses›Ebolaviruses/filoviruses      Viruses›Influenza virus      Viruses›Newcastle disease virus      Viruses›Nipah virus      Viruses›Parainfluenza virus      Viruses›Paramyxoviruses      Viruses›Parvovirus      Viruses›Porcine reproductive and respiratory syndrome virus      Viruses›Poxviruses      Viruses›Rabies virus      Viruses›Respiratory syncytial virus      Viruses›Rift Valley fever virus      Viruses›Rotavirus  Stage of vaccine development
        Adjuvants      Clinical trials      Correlates of protection – immunomonitoring      Pre-clinical trials      Vaccine delivery