Muhammad Munir

Professor
Muhammad
Munir

Prof of Virology and Viral Zoonoses
Lancaster University
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Biography

After obtaining PhD in influenza virology at the Swedish University of Agricultural Sciences, Uppsala, I worked as a BBSRC Fellow at The Pirbright Institute on NDV and Innate Immunity. Currently, Muhammad Munir is a Professor of Virology at Lancaster University in the Northwest of England, UK. Prof Munir has been studying virus pathobiology, viral antagonism of immune responses, and host factors that limit virus replication for the last 15 years. Owing to his extensive research on Newcastle disease virus (NDV), including proprietary vector establishment, Prof Munir is a leading figure in the NDV-based vaccine development. Molecular Virology Laboratory of Prof Munir holds an HSE-compliant CL3 facility, an egg incubation facility, and viral vectors. He also acts as a Technical Advisor for pharmaceuticals and supports novel product development for both humans and animals. Prof Munir has promoted the public understanding of viruses and zoonoses, presenting over 1000 times on CNN, BBC, SkyNews, ITV, Al-Jazeera, GBNews, among others, on both national and international forums. Prof Munir has won the Dean’s Award 2022 and Research Impact Award 2022 for his research excellence on viruses. Prof Munir is the author of >175 articles, 8 books, 25 book chapters, and is the Associate Editor of Scientific Reports and Microbial Pathogenesis, and Editor of Hosts and Viruses amongst others.

Research interests

I am virologist with research experience on virus pathobiology, viral antagonism of immune responses and host factors that limit virus replication. Research in my laboratory focuses on understanding molecular mechanisms of inter-species pathogenesis of viruses (i.e zoonotic viruses). Specifically, using model influenza viruses, my research aim to explore host and viral RNA biology (sensing – interferon responses, epigenetics and gene regulation) and define structural and functional differences in human and animals (e.g. birds and bats), which determine the transmission dynamics of animal viruses to human. In collaboration with national and international virologists, I study differential virus pathobology, diagnosis and vaccine developments against viruses in different animal hosts with special focus on Newcastle disease virus, a paramyxovirus causing enormous economic losses in the poultry, well-characterized vaccine vector and carrying excellent oncolytic properties. More information on this virus. My laboratory is funded by the BBSRC, British Council, Newton Fund, and Royal Society, and is equipped with CL3 facilities, holding avian viruses bank, chicken eggs facilities and expanding to establish vaccine vectors bank.

Projects you're working on
Structure-Guided and Economical Platform for Effective Vaccines Development 01/01/2025 → 31/12/2026 Research Development of a rapid on-site diagnostic platform for detection of foodborne pathogens in fish and shellfish production 01/12/2024 → 31/03/2026 Research Rapid and Smart Diagnostic System for Infectious Diseases 01/09/2023 → 31/08/2025 Research Inflammatory responses against viruses 08/11/2021 → 30/01/2023 Research Nasal Cannabinoids in Covid-19/viral pathobiology 01/08/2021 → 30/04/2022 Research Functional Validation and Safety of Antimicrobial Properties of an Innovative Coating Material 01/07/2021 → 30/06/2025 Research Low-cost Portable Molecular Diagnostic Platform for Rapid Detection of Poultry Infectious Pathogens 01/04/2021 → 30/09/2021 Research Evaluation of CoVID-19 Diagnostic Kits on Anonymized Human Samples 18/01/2021 → 31/05/2021 Research Development of CRISPR/Cas9 base Novel Poultry Vaccines against Endemic Viruses (PhD student: Julianne Vilela) 01/02/2020 → 31/03/2024 Research Establishing Field Data-Driven Vaccine Platform for Newcastle Disease Virus in Poultry: Step Towards Poverty Alleviation & Food security in Kenya 01/05/2018 → 30/04/2019 Research Effective Diagnostics and Novel Vaccine Strategies for the Control of Multiple Respiratory Viral Infections in Egyptian Poultry 01/04/2018 → 28/02/2021 Research Emerging and Next Generation Vaccine Strategies Against Veterinary Viruses 01/04/2018 → 28/02/2019 Research Low-cost Portable Molecular Diagnostic Platform for Rapid Detection of Poultry Infectious Pathogens 01/04/2018 → 31/03/2021 Research Dissecting Essential Roles of Chicken Interferon Stimulated Genes in the Pathobiology of Poultry Viruses 02/03/2018 → 01/03/2019 Research
Discipline
Bioinformatics Immunology – innate Virology
Host species
Poultry Small ruminants Zoonoses
Pathogen
Viruses VirusesCoronavirus VirusesFoot-and-mouth disease virus VirusesInfluenza virus VirusesNewcastle disease virus VirusesNipah virus VirusesParainfluenza virus VirusesParamyxoviruses VirusesPeste des petits ruminants virus VirusesRabies virus
Stage of vaccine development
Adjuvants Pre-clinical trials Vaccine delivery