Muhammad Bashir Bello

Dr
Muhammad Bashir
Bello

Head of Vaccine Research and Development
Center for Advanced Medical Research and Training, Usmanu Danfodiyo University Sokoto
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Biography

I hold a PhD degree in Vaccinology from Institute of Bioscience, Universiti Putra Malaysia where I developed and patented a recombinant live attenuated Newcastle disease virus vaccine using reverse genetics technology. I am highly skilled in several cutting edge biomedical laboratory techniques such as realtime time PCR, genomic sequencing, cell culture, molecular cloning, CRISPR-Cas9 genome editing, protein expression, vaccine efficacy/safety and many others. Furthermore, my undiluted experience in the development of recombinant DNA, viral vectored or protein subunit vaccine earned me a number of competitive research grants including the National Research Fund grants for TETFUND Nigeria, to develop next generation vaccines against emerging infectious diseases such as Lassa fever and COVID-19. I have also won the 2022 International Foundation of Science(IFS) research grant, to investigate the molecular diversity of some avian respiratory viruses in Northwestern Nigeria. Currently, I am a Senior Research Associate (Vaccinology and Molecular Virology) at the Center for Advanced Medical Research and Training, Usmanu Danfodiyo University Sokoto, where I head the Unit of Research, Diagnostics and Consultancy services. I am also a member of the Nigeria COVID-19 Research Coalition where I co-lead the Candidate vaccine subgroup. Additionally, I am a member of Nigeria Governors Forum COVID-19 Technical Advisory Group (NGF-CTAG) from 2021 to Date. I also serve as a member Grants management Office, Central Veterinary Research Laboratory Management Committee, Standing committee on Infectious Diseases as well as the management team of the TETFUND Center of Excellence in Urology and Nephrology, Usmanu Danfodito University Sokoto.

Research interests

Reverse vaccinology and innate immune mechanisms of virus clearance

Projects you're working on

1. Molecular and biological characterisation of avian respiratory viruses in northwestern Nigeria 2022-date

2. Construction and evaluation of novel COVID-19 vaccines using recombinant DNA and engineered viral vector platforms 2021-date

3. Development of a recombinant DNA vaccine for the prevention of Lassa fever in Nigeria 2021-date

Discipline
Bioinformatics Immunology – B-cells Immunology – T-cells Immunology – innate Molecular biology Virology
Host species
Poultry Small ruminants Zoonoses
Pathogen
Viruses VirusesCrimean-Congo haemorrhagic fever virus VirusesEbolaviruses/filoviruses VirusesInfectious bursal disease virus VirusesNewcastle disease virus VirusesParamyxoviruses VirusesPeste des petits ruminants virus
Stage of vaccine development
Adjuvants Antigen discovery and immunogen design Correlates of protection – immunomonitoring Vaccine delivery