Paul
Wigley
I have a BSc (Hons) in Immunology and a PhD in molecular Microbiology. I was a PDRA at the Institute for Animal Health Compton from 1998-2004 working on the immune response to Salmonella in the chicken. I joined the University of Liverpool as a Lecturer in 2005, becoming Professor in 2013. I am the reviews editor for Avian Pathology and sereved on BBSRC Committee A (Animal Health and Welfare 2011-2016). During my time at Liverpool I developed and led the MSc in Veterinary Infection and Disease Control for 9 years and currently In am involved in teaching on Veterinary, Medical and Life Sciences degree programmes.
Recent relevant publications
B lymphocytes play a limited role in clearance of Campylobacter jejuni from the chicken intestinal tract (2017) LaCharme-Lora et al. Scientific Reports 7 45090
Genome-wide fitness analyses of the foodborne pathogen Campylobacter jeuni in in vitro and in vivo models. (2017) De Vries et al. Scientific Reports 7 1251
Genome-wide association studies of immune, disease and production traits in indigenous chicken ecotypes (2016) Psfidi et al. Genetics Selection Evolution 48 74
Cytokine responses in birds challenged with the foodborne pathogen Campylobacter jejuni implies a Th17 response (2016) Reid., et al. Royal Society Open Biology 3 150451
Distinct Salmonella Enteritidis lineages associated with enterocolitis in high-income settings and invasive disease in low-income settings (2016) Feasey et al., Nature Genetics doi:10.1038/ng.3644
Paul Wigley is Professor of Avian Infection and Immunity. His research focuses on bacterial infections of poultry and the avian immune system and in particular intestinal immunity. We work in three key areas: 1. The biology of the foodborne bacterial pathogens Salmonella and Campylobacter and their control in the chicken. 2. Bacterial pathogens of poultry including APEC and Salmonella Gallinarum 3. The avian intestinal microbiome and gut health We have expertise in infection models, immunology, host and pathogen genomics and epidemiology. We utilise these in conjunction with colleagues including mathematical modellers to understand both health and disease in the chicken and to develop controls to reduce the burden of disease. Our work is focussed both on the commercial poultry production sector and backyard or village production with experience of such extensive systems in East Africa and South America We work closely with a range of industrial partners including joint projects and consultancy.