Andrew Barnes

Dr
Andrew
Barnes

Associate Professor, Aquatic Animal Health
The University of Queensland
Biography

Dr Andy Barnes obtained his BSc (Hons) in Microbiology from Heriot-Watt University, Edinburgh and his PhD from the Medical School, University of Edinburgh. Andy worked for the Scottish Office Agriculture and Fisheries Department and at the Moredun Research Institute, Edinburgh before joining a small Canadian biotech company, Aqua Health Ltd, specialising in vaccines for aquaculture in 1993. In 1999, Aqua Health was bought by Swiss pharmaceutical giant Novartis and Andy worked in their animal health division for 4 years before beginning an academic career at The University of Queensland. Currently in the School of Biological Sciences, Andy’s Aquatic Animal Health Lab researches vaccines for the aquaculture industry and investigates health and immunity in aquatic animals ranging from reef-building corals, through prawns and oysters, to barramundi, stingrays and grouper.

Research interests

My research interests lie at the interface between bacterial evolution and evolution of host adaptive immune response. Using a combination of sequencing technologies with phenotypic experiments we try to understand what makes a pathogen and how it adapts over time and under selection by the immune and non-immune host.

Projects you're working on

Bacterial genomics as a diagnostic and epidemiological tool; Adjuvants for warm and tropical water fish species; Nodavirus subunit vaccine field trials; Photobacterium and Vibrio vaccine clinical and field trials; Pathogen evolution; Host response; Tools for determining immunological status of warm water and tropical fish; Improved feeds for temperature stress in aquaculture;

Discipline
Bacteriology Bioinformatics Challenge model development Challenge study design Clinical trials – efficacy Clinical trials – safety Epidemiology Immunology – B-cells Immunology – T-cells Immunology – innate Molecular biology Protein biology
Host species
Fish
Pathogen
Bacteria BacteriaAeromonas BacteriaYersinia
Stage of vaccine development
Adjuvants Antigen discovery and immunogen design Clinical trials Correlates of protection – immunomonitoring Deployment Field trials Pre-clinical trials Vaccine delivery