My research interest focused on the preventive measures mainly development of vaccine (Divalent & Polyvalent) against the Antimicrobial Resistance Bacteria, that includes the significant pathogens such as Streptococcus spp., Aeromonas spp., Vibrio spp., affecting Aquaculture in low to middle income countries with main theme of development of oral vaccine and also the effective ways of delivery system that includes Oral, IP & immersion. Also, I enlighten my concerns towards Nano conjugated and effective biological adjuvants for the enhancement of the innate immune response in the Fin Fish Aquaculture and vaccine effect in vertical transmission research studies in brooders to the young one, which includes the plant-based vaccine for AMR stains help to attain the one health approach suggested by the WHO.