Perle LATRE DE LATE

Dr
Perle
LATRE DE LATE

Researcher
University of Missouri
Biography

Originally from Gabon and being a French citizen, Perle studied in France obtaining a BSc and an MSc(1) Cell Biology and Physiology from the University of Sciences and Technologies of Lille, an MSc(2)  Biology and Therapeutic Functions (with specialization in immunology) from the University of Paris XI and her PhD in molecular and cellular biology. For nearly 4 years, she worked in the development, function and pathology of the adrenal cortex at the Institute of Molecular and Cellular Pharmacology (Nice, France). Her project aimed to uncover the critical role of overexpression of the transcription factor SF-1 and its target genes in the pathogenesis of adrenocortical tumors. Further,  Dr. Latre de Late had the opportunity to work on host-pathogen interactions of Theileria annulata for 3 years at the Cochin Institute (Paris), in the laboratory of Gordon Langsley. She was appointed as a post-doctoral cell biologist in the Animal Genetics, Animal Biosciences program for 4 years at International Livestock Research Institute (Kenya). Her studies dealt with the understanding of the mechanism(s) of tolerance to Theileria parva in cattle, for a better control of East Coast fever. Currently, she works as a post-doctoral associate where her research focuses on the rickettsial diseases, more specifically on the development of vaccines.
 

Research interests
My various works are focused on understanding human and animal pathologies in order to find new therapeutic targets and improve treatments. For the investigation of biological questions, I am interested in an integrated approach combining methods of molecular and cell biology, immunological techniques, Omics tools, animal models, pharmacological and field trial studies, vaccine studies.
Projects you're working on
Currently I am working on the development of vaccines against Rickettsial diseases.
Discipline
Bacteriology Cellular biology Immunology – B-cells Immunology – T-cells Immunology – innate Molecular biology Parasitology
Host species
Cattle Dogs Small ruminants Zoonoses
Pathogen
Bacteria Parasites ParasitesTheileria annulata ParasitesTheileria parva
Stage of vaccine development
Adjuvants Field trials Vaccine delivery