Elisabeth (Elise) van der Heijden

Dr
Elisabeth (Elise)
van der Heijden

Postdoc
Department of Immunology and Infectious Diseases, Faculty of Veterinary Medicine, Utrecht University
Email 
e.m.d.l.vanderheijden [at] uu.nl
Biography

I originally trained as a veterinarian, specializing in small animal medicine, graduating from Utrecht University in the Netherlands in 2014. I undertook a PhD in (veterinary) immunology at the department of Immunology and Infectious Diseases of Utrecht University, with Prof Victor Rutten and Prof Anita Michel. My PhD focused on immunodiagnostics and vaccination for bovine tuberculosis in African buffaloes and cattle, respectively, which I carried out at the department of Veterinary Tropical Diseases of the University of Pretoria in South Africa, and completed in 2019.

I subsequently joined the group of Dr Tim Connelley, in the division of Infection and Immunity of the Roslin Institute, as a postdoctoral research associate. Here I worked on an experimental study elucidating the characteristics of protective versus non-protective T-cell responses to vaccination against Theileria parva in cattle, evaluating a broad range of immunological parameters as well as bioinformatics approaches.

I am currently back in Utrecht as an independent post-doc, working on RNAseq/bioinformatics studies evaluating host-pathogen interactions and vaccine outcomes in T. parva and Mycobacterium bovis in cattle. I am broadly interested in veterinary immunology and and as such am open to expand my work beyond these pathogens and hosts. My interests include immunodiagnostics, cell-mediated immunology, T-cell biology, host-pathogen interaction, RNAseq and bioinformatics approaches. I am keen to continue to develop my skills and expertise both in the wet lab as well as in bioinformatics.

Research interests

Immunology, Cellular Immunty, T-cell biology, Vaccinology, Mycobacterial diseases/Tuberculosis, Theileria/East Coast Fever, RNAseq/Bioinformatics

Projects you're working on

Defining the correlates of CD8+ T-cell mediated immunity in Theilera parva: Elucidation of functional differences in CD8+ T cell responses between protective and non-protective immune responses to Theileria parva vaccines.

Theileria parva attenuation project: Evaluating bulk and SC transcriptomics in T. parva infected T-cells.

Bovine tuberculosis miRNAome project: Studying the miRNAome in animals with different immunological backgrounds relating to M. bovis infection/vaccination.

Discipline
Immunology – T-cells Parasitology
Host species
Buffalo Cattle Wildlife Zoonoses
Pathogen
Parasites ParasitesTheileria parva ParasitesTicks
Stage of vaccine development
Correlates of protection – immunomonitoring