Nadeem Shabir

Dr
Nadeem
Shabir

Early Career Fellow (Wellcome Trust DBT India Alliance)
Sher-e-Kashmir University of Agricultural Sciences and Technology of Kashmir
Email 
nadeem.shabir [at] skuastkashmir.ac.in
Biography

Nadeem Shabir is currently serving as a scientist of vaccine biotechnology at Faculty of Veterinary Sciences, Sher-e-Kashmir University of Agricultural Sciences and Technology of Kashmir (SKUAST-K) and also a Wellcome trust India Alliance Early Career Fellow . He was awarded prestigious Chonbuk National University Doctoral fellowship and later received his Doctorate from College of Veterinary Medicine, Chonbuk National University, South Korea. Prior to his Doctorate, he received Master’s in Veterinary Sciences (Animal Biotechnology) and D.V.M degrees from Anand Agricultural University, India. Dr. Nadeem is recognized for development of a chimeric vaccine candidate possesing enhanced cross-protection against porcine reproductive and respiratory syndrome virus (PRRSV), for which he was awarded the Best Research Award by Korean Society of Veterinary Sciences in 2013. Furthermore, he has gained an expertise in studying the immunological response of PRRSV in vitro and in vivo. His expertise also involves enhancement of genetic stability of RNA viruses through mutagen-driven lethal mutagenesis. He was recently awarded a grant of about $230,000 by the Wellcome trust India Alliance for developing a recombination- as well as mutation-resistant vaccine platform against Infectious Bronchitis virus. He was also awarded a grant of $61,000 by Science and Engineering Research Board, Dept. of Science and Technology, Govt. of India under the Early Career Award scheme with an aim to develop a genetically stable live vaccine candidate against Infectious bursal disease virus that is reported to have caused huge economic impact on poultry industry worldwide. To gain a holistic view of host-pathogen interaction, Dr. Nadeem has also studied the effect of various host genotypes on immunological measures elicited in response to PRRSV infections to derive an association between host genotypes and disease resistance. He is currently a referee of various prestigious scientific journals like, Veterinary Microbiology, BMC Veterinary Research, BMC Virology Journal, Viral Immunology, Veterinary World and Pathogens (MDPI). He has also been a member of reputed scientific societies like American Society for Virology, International Pig Veterinary Society, and Korean Society of Veterinary Sciences etc

Research interests

Enhancing genetic-stability and cross-protectivity of modified live Porcine Reproductive and Respiratory Syndrome Vaccines. Regulating reversion-to-virulence events in modified live Infectious bursal disease vaccine, and live infectious bronchitis vaccine using reverse genetics and lethal mutagenesis procedures.

Projects you're working on

1. Generation of a genetically-stable live vaccine candidate against Infectious bursal disease  virus through mutagen-driven lethal mutagenesis.

2. Regulating reversion to virulence in live attenuated infectious bronchitis virus vaccine by enhancing its genetic stability. 

Host species
Pigs Poultry
Pathogen
BacteriaSalmonella Viruses VirusesCoronavirus VirusesInfectious bursal disease virus VirusesPorcine reproductive and respiratory syndrome virus