Irene Ogali

Dr
Irene
Ogali

Research Officer
Kenya Agriculture and Livestock Research Organization
Email 
inogali [at] yahoo.com
Biography

Dr. Irene Nafula Ogali

Research Officer

Kenya Agriculture and Livestock Research Organization (KARLO)

Veterinary Science Research Institute (VSRI),

Muguga, Kenya

Dr. Irene Nafula Ogali has a PhD in Biotechnology (Microbiology option) from the Jomo Kenyatta University of Agriculture and Technology, Kenya. She holds a Master of Science degree in Tropical Animal Health from the Institute of Tropical Medicine, Antwerp Belgium. Irene undertook her Bachelor’s degree in Veterinary Medicine at the University of Nairobi between 1999 and 2004. She joined Kenya Agriculture Research Institute (KARI) as a research assistant in 2005. Irene is currently a Research Officer at KALRO and the In-charge of Molecular Laboratory at the Veterinary Science Research Institute-KALRO for which she has been charged with the responsibility of strengthening and improvement of laboratory-based research at VSRI.

For the past 6 years, Irene has been actively involved in research in avian viral diseases. Irene working as an assistant poultry advisor of the International Network for Family Poultry Development researched on disease constraints affecting commercialized family poultry enterprises on Pemba Island, Tanzania. Latter she was involved in testing the efficacy of the thermostable, I2 vaccine in rural smallholder poultry in Western Kenya. Her PhD project, involved characterization of the molecular diversity of avian paramyxoviruses in Kenya, a project funded by IFS and NACOSTI. Irene has also worked on “Metagenomic Characterization of Viral Diversity in domestic pigeons in Kilifi, Kenya as an African Bioscience Challenge Fund Fellow at BeCA/ILRI Hub.

Irene has interest in the development of vaccines against viral poultry diseases for their effective control. Specifically, Dr. Ogali is interested in development of genotype-matched vaccines against Newcastle disease and Infectious bursal disease

Contacts: inogali@yahoo.com; ireneogali@yahoo.com;

Research interests

My research interest is virology, molecular biology  and vaccine development towards the control of important viruses in Kenya. Particularly I have interest in both emerging and neglected viral diseases of economic importance such as Newcastle disease virus, Infectious bursal disease, fowl pox and infectious bronchitis viruses.  I have a particular interest in use of molecular tools in understanding avian viruses in relation to their hosts, their ecology, diversity and evolution. But also have a keen interest in the design and development of vaccines that could control these key diseases

Projects you're working on

 I am working on the molecular characterization of avian viruses in Kenya in order to identify unique signatures for future development of genotype matched vaccines.  I am also working on a project on to investigate the efficacy of commercially available vaccines against Infectious bursal disease in Kenya.  I am also working on the development of a genotype-matched vaccine against Newcastle disease

Discipline
Bioinformatics Cellular biology Challenge model development Challenge study design Clinical trials – efficacy Clinical trials – safety Formulation technology Molecular biology QC test development Quality assurance Safety evaluation Structural biology Systems biology Virology
Host species
Camels Pigs Poultry Small ruminants
Pathogen
BacteriaChlamydophila ParasitesEimeria Viruses VirusesAvian papillomavirus VirusesBluetongue virus VirusesCapripoxvirus VirusesChicken anaemia virus VirusesCoronavirus VirusesFoot-and-mouth disease virus VirusesInfectious bursal disease virus VirusesMareks disease virus VirusesNairoviruses VirusesNewcastle disease virus VirusesParamyxoviruses VirusesPoxviruses VirusesRotavirus
Stage of vaccine development
Adjuvants Antigen discovery and immunogen design Clinical trials Correlates of protection – immunomonitoring Field trials Pre-clinical trials