Michael Francis

Dr
Michael
Francis

Managing Director
BioVacc Consulting Ltd
Email 
mike.francis [at] biovacc.com
Biography

Michael Francis has over 40 years of experience in vaccine research and development and has published more than 125 scientific papers. He obtained his PhD in viral immunology from the University of Surrey, UK, and began his scientific career at the Wellcome Foundation Foot-and-Mouth Disease Vaccine Laboratories, where he conducted research on the immune response to FMD vaccination. He later joined Wellcome Biotechnology Ltd and investigated novel vaccines for both human and veterinary diseases, with a particular emphasis on peptide vaccines. Dr Francis then moved to Pitman-Moore and enjoyed a progressive career with Mallinckrodt Veterinary, Schering-Plough Animal Health, Intervet/Schering-Plough and MSD/Merck Animal Health. During this time he progressed to become Executive Director and Head of Research and Development within the UK, and took on responsibility for a broad range of veterinary vaccine projects against viral, bacterial and parasitic diseases, leading to the development of successful commercial vaccines for all major domesticated veterinary species (including three vaccines against animal coronaviruses). Michael is currently the Managing Director of a specialist vaccine consultancy, BioVacc Consulting Ltd. He was elected as a Fellow of the Royal Society of Biology and awarded an Honorary Associateship of the Royal College of Veterinary Surgeons, in recognition of his contribution to the field of vaccine development and animal wellbeing. In addition he is currently a scientific editor of the journal “Research in Veterinary Science” and a member of the Zoonoses and Emerging Livestock Systems Independent Programme Advisory Group (ZIPAG), the UK Vaccine Network, an Independent Member of the UK Science Partnership for Animal and Plant Health, a Trustee of the Jenner Vaccine Foundation, a Member of the the Zoonosis and a One Health Approach (ZOOH) Advisory Group and a Board member of the International Veterinary Vaccinology Network (IVVN).

 

Research interests

Vaccine Development

Infectious Diseases

Discipline
Bio-manufacturing Challenge study design Clinical trials – efficacy Clinical trials – safety Commercialisation Deployment Formulation technology Immunology – B-cells Immunology – T-cells QC test development Quality assurance Registration Regulation Safety evaluation Virology
Host species
Camels Cats Cattle Dogs Fish Horses Pigs Poultry Small ruminants Zoonoses
Pathogen
Bacteria BacteriaBrucella BacteriaClostridia BacteriaE. coli BacteriaErysipelas BacteriaLeptospira BacteriaM. hyo BacteriaMycobacteria bovis BacteriaSalmonella BacteriaYersinia Parasites ParasitesEimeria ParasitesNematodes Viruses VirusesAdenovirus VirusesBovine viral diarrhoea VirusesCalicivirus VirusesCoronavirus VirusesFeline leukaemia virus VirusesFoot-and-mouth disease virus VirusesHerpesvirus VirusesInfectious bursal disease virus VirusesInfectious pancreatic necrosis virus VirusesInfectious salmon anaemia virus VirusesInfluenza virus VirusesMareks disease virus VirusesNewcastle disease virus VirusesParainfluenza virus VirusesParamyxoviruses VirusesParvovirus VirusesPorcine circovirus VirusesPorcine reproductive and respiratory syndrome virus VirusesPoxviruses VirusesRabies virus VirusesRespiratory syncytial virus VirusesRetroviruses VirusesRift Valley fever virus VirusesRotavirus
Stage of vaccine development
Adjuvants Antigen discovery and immunogen design Clinical trials Commercialisation Correlates of protection – immunomonitoring Deployment Field trials Marketing Pre-clinical trials Vaccine delivery