Otto Koekemoer

Dr
Otto
Koekemoer

Head: R&D
Design Biologix
Biography
I am a virologist by training and specialised on the development of vaccines and diagnostic methods for several arboviruses of veterinary importance for almost 30 years. I have a PhD in Biochemistry that I obtained in 2004 and published in several in peer-reviewed scientific journals. I also supervised five post-graduate students for masters and doctoral degrees. Previously I was appointed international expert of the OIE(WOAH) reference laboratory for African horsesickness at Onderstepoort. Over the last five years I have been involved in the R&D of veterinary vaccines at commercial manufacturing facilities. I am currently employed at Design Biologix in South Africa where I lead a team involved in the development, testing, and process optimisation for novel and improved veterinary vaccines.
Research interests
Veterinary vaccines: development, prototype testing, clinical trials, Production process development and validation QC method development and validation Vaccine registration
Discipline
Bacteriology Bio-manufacturing Challenge study design Clinical trials – efficacy Clinical trials – safety Commercialisation Formulation technology Molecular biology Parasitology Pharmacovigilance QC test development Quality assurance Registration Safety evaluation Virology
Host species
Cats Cattle Dogs Horses Small ruminants Zoonoses
Pathogen
BacteriaBrucella BacteriaChlamydophila BacteriaClostridia Parasites Viruses VirusesAfrican horse sickness virus VirusesArboviruses VirusesBluetongue virus VirusesBovine ephemeral fever virus VirusesBovine viral diarrhoea VirusesCapripoxvirus VirusesInfectious bursal disease virus VirusesRift Valley fever virus
Stage of vaccine development
Adjuvants Clinical trials Commercialisation Field trials Marketing Pre-clinical trials Vaccine delivery