Projecting vaccine demand and impact for emerging zoonotic pathogens

16 Jun 2022
Lerch A, Ten Bosch QA, L'Azou Jackson M, Bettis AA, Bernuzzi M, Murphy GAV, Tran QM, Huber JH, Siraj AS, Bron GM, Elliott M, Hartlage CS, Koh S, Strimbu K, Walters M, Perkins TA and Moore SM

Despite large outbreaks in humans seeming improbable for a number of zoonotic pathogens, several pose a concern due to their epidemiological characteristics and evolutionary potential. To enable effective responses to these pathogens in the event that they undergo future emergence, the Coalition for Epidemic Preparedness Innovations is advancing the development of vaccines for several pathogens prioritized by the World Health Organization. A major challenge in this pursuit is anticipating demand for a vaccine stockpile to support outbreak response.